Intersection: Huntington and poverty in the Latin-American clusters

Huntington’s disease (HD) is a genetic, fatal, and progressive neurodegenerative disease. HD does not discriminate based on ethnicity or gender. It advances slowly, but relentlessly. The disease is caused by mutations in a single gene, called Huntingtin, and the penetrance of the mutation is 100%.  If one is born with a Huntingtin mutation, today one will die from Huntington’s […]

State of Therapeutic Programs

From a gene mutation to a lethal disease HD is caused by a single mutation in a region of the HTT gene, located at the beginning of the gene (in exon 1), which contains a repeat sequence comprised of CAG repeats; in the normal range, people have between 17-22 repeats on average; in HD individuals, […]