Author: Ignacio Munoz

Stem cells and HD drug discovery

Last week, CHDI hosted a stem cell meeting in Princeton, NJ, chaired by Thomas Vogt (CHDI’s new VP for Discovery & Systems Biology), and myself. We hosted several eminent scientists working on the use of stem cells for understanding HD pathogenesis, and identifying new mechanisms for potential therapeutic treatments. The meeting did not cover the […]

Articulo sobre Juan de Acosta en Colombia

La poblacion de la EH de Juan de Acosta es una de las poblaciones mas grandes del mundo en cuanto a prevalencia de la enfermedad. Hace algo mas de un año visite a esta comunidad en Colombia, donde me reuni con el Dr. Daza, el neurologo que llevaba tratando a los pacientes locales desde hace […]

clothes donated by Factor-H arrive in the communities in Colombia

500 pounds (300+ kilograms) of donated clothes have arrived at several communities in Colombia. Thanks to the Conexion Colombia NGO (www.conexioncolombia.com) , all the donated clothes Factor-H collected in Los Angeles have made it to their destinations. This is the first ‘international’ shipment of donated goods to benefit the Colombian families. we Hope that in […]

Human genetics research sheds new hope in modulating the progression of HD

Human genetics research sheds new hope in modulating the progression of HD MAR23 2014 It is not unfair to say that almost the entire field of therapeutic development for the treatment of HD is founded on the learnings that stem from the cloning of the gene causative of HD, the huntingtin gene. As a monogenic disorder […]

Factor-H delivers clothes to San Luis neighborhood in Maracaibo, Venezuela

Last week, Claudia and I from Factor-H, together with the Venezuelan physicians and patient association (Avehun), we spent a day visiting the neighborhood of San Luis, outside Maracaibo. We hand-delivered clothes donated by our US friends and colleagues, to about 50 people living with HD in their families. It was a day where at least […]

PLEASE DONATE TO HABITAT FOR HUMANITY HD PROJECT IN COLOMBIA!

  NOV 06 2013 PLEASE CONSIDER MAKING A DONATION. Habitat for humanity and Factor-H, my other ‘job’, started a collaboration together with the Colombian family association (AcolpEH), to raise funds for patients living in suboptimal conditions in Colombia. Find the link here: http://share.habitat.org/fighting-huntingtons We are very behind, and we need your help. So if you […]

Pfizer’s PDE10 inhibitor enters clinical trials for HD

Pfizer’s PDE10 inhibitor enters clinical trials for HD JUN16 2013 This is a good year for HD, and for all working to develop medicines to treat all those affected. For the first time in CHDI’s existence, a clinical trial with a new drug entity will start this month. The collaboration between CHDI and Pfizer began […]

The importance of biomarkers

As I have described before, the age of molecular therapies for the treatment of HD is around the corner. But a critical component of the drug development process is still lacking: the identification of Htt-dependent biomarkers. Why is this important? Imagine what will happen over the next 1-3 years. Several of the molecular therapeutics aimed […]

New center opens in Santiago!

Dear all- today marks a historic day in the solidarity with the patients and their families in Chile and in all of Latinamerica- the Chilean HD association together with its collaborators have inugurated a center for the care of people affected with HD. Claudia Perandones attended the opening ceremony in Santiago. Rodrigo Osorio, the president […]